Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies.

For our Toulouse site, we are looking for a highly motivated

PhD - Expert in mass spectrometry for screening projects (M/F)

Missions

Under the responsibility of a group leader in the “High Throughput Biology and Screening department”, you will be part of a team responsible for development and realization of Mass Spectrometry based screening.

Project management

• Contribute to screening projects, from assay development to screening campaign: define, execute and/or coordinate experimental processes and data analysis.
• Optimize and miniaturize screening assays.
• Plan and realize screening campaigns in close collaboration with the group leaders.
• Analyze experimental results in their biological context in collaboration with screening, bio-informatics and biostatistics teams.
• Ensure compliance to the specifications agreed with the customer
• Contribute to the elaboration and the execution of new methodologies and strategies applied to high throughput screening, in particular for mass spec based assays.

Communication and information

• Monitor scientific and technical development in the domain of activity.
• Prepare study reports and communicate scientific results to customers.

Quality

• Ensure quality and reliability of scientific results.
• Ensure good laboratory practices and health and safety instructions.

Role and Responsibilities

• Prepare and execute screening studies according to the specifications agreed with the customer.
• You are responsible for biological and biophysical result analysis and interpretation.
• You are responsible for the quality and reliability of scientific results.

Knowledge and abilities

            required :

• Strong expertise in mass spectrometry (High resolution and MS/MS)
• Excellent background in separation technologies (SPE/RapidFire – HPLC)
• Good understanding of cellular biology, biochemistry (enzymology) and biophysics (affinity assay)
• Experience in planning and monitoring scientific projects
• Written and oral communication skills
• Meet good laboratory practices and health and safety instructions.
• Transversal team spirit, rigor, dynamism and autonomy.
• Good written and spoken communication in French and English.

            preferred :

• Experience in SEC-LC/MS and RapideFire MS/MS
• Expertize in biophysics
• Experience in screening projects & automation 
• Experimental data interpretation, and analysis of large sets of data.

Training and experience

• PhD in biology or chemistry.
• 0-3 year postdoc experience in academia or industry in mass spectrometry area.